This marks a 13 per cent increase over the previous record.
The surge in passenger numbers was largely due to the popularity of Amsterdam, which was the most popular destination for the first time this year.
More than 95,000 passengers flew to or from the Dutch capital in November.
However, Dublin was the most popular destination in November.
Many travellers sought winter sun in warmer European locations such as Tenerife, Lanzarote, and Alicante, as well as Middle Eastern destinations like Dubai and Qatar.
The airport is preparing for a busy festive season, with 1.1 million passengers expected to travel during the two weeks over Christmas and New Year.
This includes 25,000 passengers heading to Lapland, with flights launched to five Finnish airports not usually served during the rest of the year.
The Finnish airports in Ivalo, Kittila, Enontekio, Kuusamo, and Rovaniemi join Manchester’s route network in December, providing access to the ‘winter wonderland’ of Lapland.
Manchester Airport managing director Chris Woodroofe said: “Christmas is a magical time here at Manchester Airport.
“We’re always proud to connect the North to the world but the importance of that role really shines through at this time of year.
“It feels wonderful when you see travellers having emotional reunions in arrivals and families in departures getting ready to visit Father Christmas in Lapland.
“It’s also always a popular time to fly and, having broken our passenger records every month for well over a year now, we expect this Christmas to be the biggest and busiest we’ve ever seen with over a million passengers flying in the two-week festive period.”
November data shows that 99 per cent of passengers waited for 15 minutes or less to get through security, and 82 per cent waited for under five minutes.
The airport is also wrapping up its transformation programme, which started in 2015 and is set to be completed next year.
The first work to build a new road near Terminal 2 has begun, with ground broken on the project to build Sydney Avenue, a new link road near the Thorley Lane entrance to the airport site.
This will replace the existing Sydney Avenue and aims to improve traffic flow in the area.
The first trials of new taxiways on the airfield have been successfully completed.
The new taxiways allow large aircraft to pass side by side en route to Terminal 2, marking a ‘significant step’ in opening the full capacity of the new terminal.
External work on the new pier on Terminal 2, the second pier, has also been completed, taking it a step closer to completion.
The piers on the terminal are structures that extend from the main building and are home to the gates where passengers embark and disembark.
Some of the retail spaces in the new part of the terminal have been handed over to the brands that will run them, so they can be fitted out and ready to open next year.
Mr Woodroofe said: “Not only will those passengers receive a great service – last month 82 per cent of our passengers waited less than five minutes to get to security – but they will also be able to soak up some of the magic we have here, including Santa’s grotto in our Little Flyers Zone in Terminal 1 and choirs singing carols at various spots in all three terminals.
“We can’t wait to welcome passengers to Manchester Airport this festive season.”
